Muscle spasms and creatine phosphokinase elevation following salbutamol administration.

The drug of choice for the treatment of occasional acute symptoms of asthma is an inhaled beta adrenergic agonist, such as salbutamol. The most frequent adverse reactions to salbutamol include nervousness, headache, tremor, tiredness and light-headedness [1]. The following report describes a patient with asthma from childhood, who developed creatine phosphokinase elevation associated with severe muscle spasms following oral and inhaled salbutamol administration.